Scalp Mesotherapy vs PRP for Hair Loss

Compare what scalp mesotherapy and PRP contain, what research shows for pattern hair loss and which questions to ask before choosing a course of injections.

Illustrative scalp mesotherapy assessment

PRP uses a sample of your own blood to prepare platelet-rich plasma for scalp injections. Mesotherapy describes a way of injecting a preparation into the scalp. Its ingredients can vary between products. To compare the two for hair loss, you need the diagnosis and the name and ingredients of the proposed preparation.

Start with the pattern of hair loss

A slowly widening parting raises different questions from a sudden episode of shedding or a new bald patch. Tell the clinician when the change began, whether the scalp is painful or inflamed and whether you have recently been unwell. A GP or dermatologist can assess an unexplained change before you consider injections.

If there is a diagnosis of pattern hair loss, agree on the goal. Slower thinning, an increase in measured density and regrowth over a bare area are very different expectations. Ask which one the evidence supports in a situation like yours.

What goes into the scalp?

For PRP, the practitioner takes blood, separates a platelet-rich portion and uses it for treatment. Preparation methods and appointment schedules vary. Ask how the practitioner will check that you are suitable for both the blood draw and the injections.

For mesotherapy, request the exact product name and ingredients before booking. If a medicine is included, ask who prescribes it and how its use and possible side effects apply to you. A study of a different mixture gives limited guidance about the one being offered.

What does a study result mean for an individual?

A randomised trial in women with pattern hair loss reported improved hair density with PRP compared with placebo. That finding concerns a particular diagnosis, preparation and period of follow-up. It cannot tell you whether your own hair will visibly thicken or how long a change might last.

One randomised mesotherapy study in men compared a particular preparation with topical minoxidil. That is a different question from comparing the same preparation directly with PRP. Ask to see evidence for the product, the type of hair loss and the outcome that matters to you before choosing a course.

What to agree before the first visit

Tell the clinician about allergies, medicines, bleeding problems, previous reactions and scalp infections. Both procedures involve skin punctures, with possible soreness, bruising, bleeding or infection. Mesotherapy also requires a discussion of ingredient-specific risks. Ask for aftercare details and a contact if the scalp becomes increasingly painful or inflamed.

Decide how progress will be assessed before committing to repeat visits. Comparable photographs or repeat measurements of the same area can help. Ask for the total proposed fee, the review date and what would lead the practitioner to stop, change approach or refer you for further assessment.

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Sources & further reading

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